Resins for Oligonucleotide Synthesis

B6 Resins for Oligonucleotide Synthesis

• TentaGel® N Resins

B6.1 Base TentaGel® N Resins

貨號	名稱	particle size	capacity	包裝
N 30 000	TentaGel® N OH	90 µm	200 - 250 µmol/g	1g
N 30 000	TentaGel® N OH	90 µm	200 - 250 µmol/g	5g
N 30 000	TentaGel® N OH	90 µm	200 - 250 µmol/g	25g
N 30 002	TentaGel® N NH?	90 µm	200 - 250 µmol/g	1g
N 30 002	TentaGel® N NH?	90 µm	200 - 250 µmol/g	5g
N 30 002	TentaGel® N NH?	90 µm	200 - 250 µmol/g	25g

B6.2 Preloaded TentaGel® N Resins

貨號	名稱	particle size	capacity	包裝
N 30 002-1	TentaGel® N A	90 µm	170 - 220 µmol/g	1g
N 30 002-1	TentaGel® N A	90 µm	170 - 220 µmol/g	5g
N 30 002-1	TentaGel® N A	90 µm	170 - 220 µmol/g	25g
N 30 002-2	TentaGel® N C	90 µm	170 - 220 µmol/g	1g
N 30 002-2	TentaGel® N C	90 µm	170 - 220 µmol/g	5g
N 30 002-2	TentaGel® N C	90 µm	170 - 220 µmol/g	25g
N 30 002-3	TentaGel® N G	90 µm	170 - 220 µmol/g	1g
N 30 002-3	TentaGel® N G	90 µm	170 - 220 µmol/g	5g
N 30 002-3	TentaGel® N G	90 µm	170 - 220 µmol/g	25g
N 30 002-4	TentaGel® N T	90 µm	170 - 220 µmol/g	1g
N 30 002-4	TentaGel® N T	90 µm	170 - 220 µmol/g	5g
N 30 002-4	TentaGel® N T	90 µm	170 - 220 µmol/g	25g

²B7 Resins with Linkers

B7.1 Bromo Acetal Resins

B7.1.1 HypoGel® Bromo Acetal Resins
HypoGel® is a hydrophilic gel type resin which combines high capacities with good solvent compatibility. Glycol spacers with n = 5 or 10 EO units separate the reactive sites from the polystyrene matrix and modify the hydrophobic properties of the polystyrene backbone. Due to the spacer effect the functional group shows a higher mobility which results in higher kinetic rates and high resolution NMR spectra from immobilized compounds on the bead. The resin is compatible to a wide range of solvents and in contrast to polystyrene even polar solvents like methanol or ethanol can be used.
These resins show high loading and a hydrophilicity between polystyrene and TentaGel®
Reaction with primary amines generates immobilized N-substituted glycinal acetals suitable for the synthesis of heterocycles derived from 1-acyl-3-oxopiperazine.
Literature
L 17

貨號	名稱	particle size	capacity	包裝
SP200 110150 190	HypoGel® 200 Bromo Acetal	110 - 150 µm	0.75 - 0.95 mmol/g	5g
SP200 110150 190	HypoGel® 200 Bromo Acetal	110 - 150 µm	0.75 - 0.95 mmol/g	25g
SP200 110150 190	HypoGel® 200 Bromo Acetal	110 - 150 µm	0.75 - 0.95 mmol/g	100g
SP400 110150 190	HypoGel® 400 Bromo Acetal	110 - 150 µm	0.6 - 0.8 mmol/g	5g
SP400 110150 190	HypoGel® 400 Bromo Acetal	110 - 150 µm	0.6 - 0.8 mmol/g	25g
SP400 110150 190	HypoGel® 400 Bromo Acetal	110 - 150 µm	0.6 - 0.8 mmol/g	100g

B7.1.2 TentaGel® Bromo Acetal Resins
TentaGel® resins are grafted copolymers consisting of a low crosslinked polystyrene matrix on which polyethylene glycol (PEG or POE) is grafted. The PEG spacer is attached to the matrix via an ethyl ether group which increases stability towards acid treatment and minimizes PEG-leaching. As PEG is a "chameleon type" polymer with hydrophobic and hydrophilic properties, the graft copolymer shows modified physico chemical properties which are highly dominated by the PEG moiety (and no longer by the polystyrene matrix). These graft copolymers are pressure stable and can be used in batch processes as well as under continuous flow conditions. The PEG spacer is in the range of MW 3000 Da.
Reaction with primary amines generates immobilized N-substituted glycinal acetals suitable for the synthesis of heterocycles derived from 1-acyl-3-oxopiperazine.
Literature
L 4, L 5, L 6, L 7, L 24, L 25, L 47; see also: General Information

貨號	名稱	particle size	capacity	包裝
HL 12 019	TentaGel® HL Bromo Acetal	75 µm	0.4 - 0.55 mmol/g	5g
HL 12 019	TentaGel® HL Bromo Acetal	75 µm	0.4 - 0.55 mmol/g	25g
HL 12 019	TentaGel® HL Bromo Acetal	75 µm	0.4 - 0.55 mmol/g	100g

B7.2 Diol Resins

B7.2.1 HypoGel® Diol Resins

貨號	名稱	particle size	capacity	包裝
SP200 110150 10	HypoGel® 200 Diol	110 - 150 µm	1.2 - 1.5 mmol/g	5g
SP200 110150 10	HypoGel® 200 Diol	110 - 150 µm	1.2 - 1.5 mmol/g	25g
SP200 110150 10	HypoGel® 200 Diol	110 - 150 µm	1.2 - 1.5 mmol/g	100g
SP400 110150 10	HypoGel® 400 Diol	110 - 150 µm	0.9 - 1.3 mmol/g	5g
SP400 110150 10	HypoGel® 400 Diol	110 - 150 µm	0.9 - 1.3 mmol/g	25g
SP400 110150 10	HypoGel® 400 Diol	110 - 150 µm	0.9 - 1.3 mmol/g	100g

B7.2.2 TentaGel® Diol Resins

貨號	名稱	particle size	capacity	包裝
HL 12 010	TentaGel® HL Diol	75 µm	0.6 - 0.8 mmol/g	5g
HL 12 010	TentaGel® HL Diol	75 µm	0.6 - 0.8 mmol/g	25g
HL 12 010	TentaGel® HL Diol	75 µm	0.6 - 0.8 mmol/g	100g

B7.3 p - Nitrophenyl Carbonate Resin

B7.3.1 p - Nitrophenyl Carbonate on TentaGel PHB Resin
TentaGel® resins are grafted copolymers consisting of a low crosslinked polystyrene matrix on which polyethylene glycol (PEG or POE) is grafted. The PEG spacer is attached to the matrix via an ethyl ether group which increases stability towards acid treatment and minimizes PEG-leaching. As PEG is a "chameleon type" polymer with hydrophobic and hydrophilic properties, the graft copolymer shows modified physico chemical properties which are highly dominated by the PEG moiety (and no longer by the polystyrene matrix). These graft copolymers are pressure stable and can be used in batch processes as well as under continuous flow conditions. The PEG spacer is in the range of MW 3000 Da.
Amines can be attached to the p-nitrophenyl carbonate resin to form the corresponding resin bound carbamates.
Literature
L 4, L 5, L 6, L 7, L 8, L 24, L 25, L 43, L 54; see also: General Information.

貨號	名稱	particle size	capacity	包裝
S 30 050	TentaGel® S – NPC	90 µm	0.2 - 0.3 mmol/g	1g
S 30 050	TentaGel® S – NPC	90 µm	0.2 - 0.3 mmol/g	5g
S 30 050	TentaGel® S - NPC	90 µm	0.2 - 0.3 mmol/g	25g

B7.3.2 p - Nitrophenyl Carbonate on Wang Resin
Amines can be attached to the p-nitrophenyl carbonate resin to form the corresponding resin bound carbamates. As an example the following compounds were synthesized by modifications on the resin bound carbamates: unsymetrical diamines, allylamines, guanidines, hydantoines, piperazines, triazolidienones, quinazoline diones ect.

貨號	名稱	particle size	capacity	包裝
H 100 50	Polystyrene Wang NPC	100 - 200 mesh	0.8 - 1.2 mmol/g	1g
H 100 50	Polystyrene Wang NPC	100 - 200 mesh	0.8 - 1.2 mmol/g	5g
H 100 50	Polystyrene Wang NPC	100 - 200 mesh	0.8 - 1.2 mmol/g	25g
H 400 50	Polystyrene Wang NPC	200 - 400 mesh	0.8 - 1.2 mmol/g	1g
H 400 50	Polystyrene Wang NPC	200 - 400 mesh	0.8 - 1.2 mmol/g	5g
H 400 50	Polystyrene Wang NPC	200 - 400 mesh	0.8 - 1.2 mmol/g	25g

B7.4 Polymer Bound Acrylic Ester (REM Resins)

These resins with the immobilized acrylic acid are supports for the SOPS of tertiary amines. The first step is a Michael addition of a primary or secondary amine followed by quarternization with the appropriate alkyl halide. b-Elimination yields the tertiary amine.
Literature
L 43
Please select a subcategory:
B7.4.1 Acrylic Ester attached to Polar PEG Spacer Resins
HypoGel® REM Resins

貨號	名稱	particle size	capacity	包裝
SP200110150 180	HypoGel® 200 REM	110 - 150 µm	0.6 - 0.8 mmol/g	5g
SP200110150 180	HypoGel® 200 REM	110 - 150 µm	0.6 - 0.8 mmol/g	25g
SP200110150 180	HypoGel® 200 REM	110 - 150 µm	0.6 - 0.8 mmol/g	100g
SP400110150 180	HypoGel® 400 REM	110 - 150 µm	0.5 - 0.6 mmol/g	5g
SP400110150 180	HypoGel® 400 REM	110 - 150 µm	0.5 - 0.6 mmol/g	25g
SP400110150 180	HypoGel® 400 REM	110 - 150 µm	0.5 - 0.6 mmol/g	100g

TentaGel® REM Resins

貨號	名稱	particle size	capacity	包裝
HL 12 018	TentaGel® HL REM	75 µm	0.3 - 0.5 mmol/g	5g
HL 12 018	TentaGel® HL REM	75 µm	0.3 - 0.5 mmol/g	25g
HL 12 018	TentaGel® HL REM	75 µm	0.3 - 0.5 mmol/g	100g

B7.4.2 Polystyrene REM Resins

貨號	名稱	particle size	capacity	包裝
HA 1 100 18	Polystyrene A REM	100 - 200 mesh	0.8 - 1.3 mmol/g	5g
HA 1 100 18	Polystyrene A REM	100 - 200 mesh	0.8 - 1.3 mmol/g	25g
HA 1 100 18	Polystyrene A REM	100 - 200 mesh	0.8 - 1.3 mmol/g	100g
HA 1 400 18	Polystyrene A REM	200 - 400 mesh	0.8 - 1.3 mmol/g	5g
HA 1 400 18	Polystyrene A REM	200 - 400 mesh	0.8 - 1.3 mmol/g	25g
HA 1 400 18	Polystyrene A REM	200 - 400 mesh	0.8 - 1.3 mmol/g	100g
HA 125160 18	Polystyrene A REM	125 - 160 µm	0.8 - 1.3 mmol/g	5g
HA 125160 18	Polystyrene A REM	125 - 160 µm	0.8 - 1.3 mmol/g	25g
HA 125160 18	Polystyrene A REM	125 - 160 µm	0.8 - 1.3 mmol/g	100g
HA 160200 18	Polystyrene A REM	160 - 200 µm	0.8 - 1.0 mmol/g	5g
HA 160200 18	Polystyrene A REM	160 - 200 µm	0.8 - 1.0 mmol/g	25g
HA 160200 18	Polystyrene A REM	160 - 200 µm	0.8 - 1.0 mmol/g	100g
HA 250315 18	Polystyrene A REM	250 - 315 µm	0.7 - 1.0 mmol/g	5g
HA 250315 18	Polystyrene A REM	250 - 315 µm	0.7 - 1.0 mmol/g	25g
HA 250315 18	Polystyrene A REM	250 - 315 µm	0.7 - 1.0 mmol/g	100g
HA 400450 18	Polystyrene A REM	400 - 450 µm	0.7 - 1.0 mmol/g	5g
HA 400450 18	Polystyrene A REM	400 - 450 µm	0.7 - 1.0 mmol/g	25g
HA 400450 18	Polystyrene A REM	400 - 450 µm	0.7 - 1.0 mmol/g	100g
HA 500560 18	Polystyrene A REM	500 - 560 µm	0.7 - 1.0 mmol/g	5g
HA 500560 18	Polystyrene A REM	500 - 560 µm	0.7 - 1.0 mmol/g	25g
HA 500560 18	Polystyrene A REM	500 - 560 µm	0.7 - 1.0 mmol/g	100g

B7.5 Resins with Acid Labile Linkers

B7.5.1 Resins for Amine and Amide Terminated Compounds
B7.5.1.1 Rink-Amide Linker on Aminoethyl Polystyrene Resins

貨號	名稱	particle size	capacity	包裝
HA 1 100 23	Polystyrene A RAM	100 - 200 mesh	0.6 - 0.8 mmol/g	5g
HA 1 100 23	Polystyrene A RAM	100 - 200 mesh	0.6 - 0.8 mmol/g	25g
HA 1 100 23	Polystyrene A RAM	100 - 200 mesh	0.6 - 0.8 mmol/g	100g
HA 1 400 23	Polystyrene A RAM	200 - 400 mesh	0.6 - 0.8 mmol/g	5g
HA 1 400 23	Polystyrene A RAM	200 - 400 mesh	0.6 - 0.8 mmol/g	25g
HA 1 400 23	Polystyrene A RAM	200 - 400 mesh	0.6 - 0.8 mmol/g	100g
HA 125160 23	Polystyrene A RAM	125 - 160 µm	0.4 - 0.7 mmol/g	5g
HA 125160 23	Polystyrene A RAM	125 - 160 µm	0.4 - 0.7 mmol/g	25g
HA 125160 23	Polystyrene A RAM	125 - 160 µm	0.4 - 0.7 mmol/g	100g
HA 160200 23	Polystyrene A RAM	160 - 200 µm	0.4 - 0.7 mmol/g	5g
HA 160200 23	Polystyrene A RAM	160 - 200 µm	0.4 - 0.7 mmol/g	25g
HA 160200 23	Polystyrene A RAM	160 - 200 µm	0.4 - 0.7 mmol/g	100g
HA 250315 23	Polystyrene A RAM	250 - 315 µm	0.4 - 0.7 mmol/g	5g
HA 250315 23	Polystyrene A RAM	250 - 315 µm	0.4 - 0.7 mmol/g	25g
HA 250315 23	Polystyrene A RAM	250 - 315 µm	0.4 - 0.7 mmol/g	100g
HA 400450 23	Polystyrene A RAM	400 - 450 µm	0.4 - 0.7 mmol/g	5g
HA 400450 23	Polystyrene A RAM	400 - 450 µm	0.4 - 0.7 mmol/g	25g
HA 400450 23	Polystyrene A RAM	400 - 450 µm	0.4 - 0.7 mmol/g	100g
HA 500560 23	Polystyrene A RAM	500 - 560 µm	0.4 - 0.7 mmol/g	5g
HA 500560 23	Polystyrene A RAM	500 - 560 µm	0.4 - 0.7 mmol/g	25g
HA 500560 23	Polystyrene A RAM	500 - 560 µm	0.4 - 0.7 mmol/g	100g

B7.5.1.2 Rink-Amide Linker on Aminomethyl Polystyrene Resins

貨號	名稱	particle size	capacity	包裝
H 100 23	Polystyrene AM RAM	100 - 200 mesh	0.6 - 0.8 mmol/g	5g
H 100 23	Polystyrene AM RAM	100 - 200 mesh	0.6 - 0.8 mmol/g	25g
H 100 23	Polystyrene AM RAM	100 - 200 mesh	0.6 - 0.8 mmol/g	100g
H 400 23	Polystyrene AM RAM	200 - 400 mesh	0.6 - 0.8 mmol/g	5g
H 400 23	Polystyrene AM RAM	200 - 400 mesh	0.6 - 0.8 mmol/g	25g
H 400 23	Polystyrene AM RAM	200 - 400 mesh	0.6 - 0.8 mmol/g	100g
H 125160 23	Polystyrene AM RAM	125 - 160 µm	0.4 - 0.7 mmol/g	5g
H 125160 23	Polystyrene AM RAM	125 - 160 µm	0.4 - 0.7 mmol/g	25g
H 125160 23	Polystyrene AM RAM	125 - 160 µm	0.4 - 0.7 mmol/g	100g
H 160200 23	Polystyrene AM RAM	160 - 200 µm	0.4 - 0.7 mmol/g	5g
H 160200 23	Polystyrene AM RAM	160 - 200 µm	0.4 - 0.7 mmol/g	25g
H 160200 23	Polystyrene AM RAM	160 - 200 µm	0.4 - 0.7 mmol/g	100g
H 250315 23	Polystyrene AM RAM	250 - 315 µm	0.4 - 0.7 mmol/g	5g
H 250315 23	Polystyrene AM RAM	250 - 315 µm	0.4 - 0.7 mmol/g	25g
H 250315 23	Polystyrene AM RAM	250 - 315 µm	0.4 - 0.7 mmol/g	100g
H 400450 23	Polystyrene AM RAM	400 - 450 µm	0.4 - 0.7 mmol/g	5g
H 400450 23	Polystyrene AM RAM	400 - 450 µm	0.4 - 0.7 mmol/g	25g
H 400450 23	Polystyrene AM RAM	400 - 450 µm	0.4 - 0.7 mmol/g	100g
H 500560 23	Polystyrene AM RAM	500 - 560 µm	0.4 - 0.7 mmol/g	5g
H 500560 23	Polystyrene AM RAM	500 - 560 µm	0.4 - 0.7 mmol/g	25g
H 500560 23	Polystyrene AM RAM	500 - 560 µm	0.4 - 0.7 mmol/g	100g

B7.5.1.3 Rink-Amide Linker on HypoGel® Resins

貨號	名稱	particle size	capacity	包裝
SP200 110150 230	HypoGel® 200 RAM	110 - 150 µm	0.6 - 0.7 mmol/g	5g
SP200 110150 230	HypoGel® 200 RAM	110 - 150 µm	0.6 - 0.7 mmol/g	25g
SP200 110150 230	HypoGel® 200 RAM	110 - 150 µm	0.6 - 0.7 mmol/g	100g
SP400 110150 230	HypoGel® 400 RAM	110 - 150 µm	0.5 - 0.6 mmol/g	5g
SP400 110150 230	HypoGel® 400 RAM	110 - 150 µm	0.5 - 0.6 mmol/g	25g
SP400 110150 230	HypoGel® 400 RAM	110 - 150 µm	0.5 - 0.6 mmol/g	100g

B7.5.1.4 Rink-Amide Linker on TentaGel® Resins
B7.5.1.4.1 TentaGel® HL RAM RAM Linker Attached to High Loaded TentaGel Resins
This highloaded version of TentaGel® combines a significantly higher capacity with the advantages of TentaGel® resins. The spacer is in the range of MW 1500 - 2000 Da.
This resin is functionalized with a modified Rink Amide linker and is ideal for the Fmoc SPPS of peptide amides. Cleavage from this support is achieved with 95 % TFA.

貨號	名稱	particle size	capacity	包裝
HL 12 023	TentaGel® HL RAM	75 µm	0.3 - 0.4 mmol/g	1g
HL 12 023	TentaGel® HL RAM	75 µm	0.3 - 0.4 mmol/g	5g
HL 12 023	TentaGel® HL RAM	75 µm	0.3 - 0.4 mmol/g	25g
HL 12 023	TentaGel® HL RAM	75 µm	0.3 - 0.4 mmol/g	100g

B7.5.1.4.2 TentaGel® MB RAM RAM Linker Attached to TentaGel Macrobeads
TentaGel® Macrobeads are highlighted by extraordinary large particle diameters and high capacities based on the TentaGel® technology and designed for single bead synthesis and single bead analysis.
This resin is functionalized with a modified Rink Amide linker and is ideal for the Fmoc SPPS of peptide amides. Cleavage from this support is achieved with 95 % TFA.
Literature
L 3

貨號	名稱	particle size	capacity	包裝
MB 160 230	TentaGel® MB RAM	140 - 170 µm	0.3 - 0.4 mmol/g	1g
MB 160 230	TentaGel® MB RAM	140 - 170 µm	0.3 - 0.4 mmol/g	5g
MB 160 230	TentaGel® MB RAM	140 - 170 µm	0.3 - 0.4 mmol/g	25g
MB 160 230	TentaGel® MB RAM	140 - 170 µm	0.3 - 0.4 mmol/g	100g
MB 250 230	TentaGel® MB RAM	200 - 250 µm	0.2 - 0.3 mmol/g	1g
MB 250 230	TentaGel® MB RAM	200 - 250 µm	0.2 - 0.3 mmol/g	5g
MB 250 230	TentaGel® MB RAM	200 - 250 µm	0.2 - 0.3 mmol/g	25g
MB 250 230	TentaGel® MB RAM	200 - 250 µm	0.2 - 0.3 mmol/g	100g
MB 250 230	TentaGel® MB RAM	280 - 320 µm	0.2 - 0.3 mmol/g	1g
MB 250 230	TentaGel® MB RAM	280 - 320 µm	0.2 - 0.3 mmol/g	5g
MB 300 230	TentaGel® MB RAM	280 - 320 µm	0.2 - 0.3 mmol/g	25g
MB 300 230	TentaGel® MB RAM	280 - 320 µm	0.2 - 0.3 mmol/g	100g

B7.5.1.4.3 TentaGel® R RAM RAM Linker Attached to TentaGel Research Resins
TentaGel® resins are grafted copolymers consisting of a low crosslinked polystyrene matrix on which polyethylene glycol (PEG or POE) is grafted. The PEG spacer is attached to the matrix via an ethyl ether group which increases stability towards acid treatment and minimizes PEG-leaching. As PEG is a "chameleon type" polymer with hydrophobic and hydrophilic properties, the graft copolymer shows modified physico chemical properties which are highly dominated by the PEG moiety (and no longer by the polystyrene matrix). These graft copolymers are pressure stable and can be used in batch processes as well as under continuous flow conditions. The PEG spacer is in the range of MW 3000 Da.
TentaGel® R represents a special designed resin for research synthesis. Long peptide sequences (up to 100 residues) and difficult sequences are synthesized on this support. The resin shows an increased swelling volume and a significant lower loading.
This resin is functionalized with a modified Rink Amide linker and is ideal for the Fmoc SPPS of peptide amides. Cleavage from this support is achieved by 95 % TFA.
Literature
L 4, L 5, L 6, L 7, L 24, L 25; ee also: General Information

貨號	名稱	particle size	capacity	包裝
R 28 023	TentaGel® R RAM	90 µm	0.18 - 0.22 mmol/g	1g
R 28 023	TentaGel® R RAM	90 µm	0.18 - 0.22 mmol/g	5g
R 28 023	TentaGel® R RAM	90 µm	0.18 - 0.22 mmol/g	25g
R 28 023	TentaGel® R RAM	90 µm	0.18 - 0.22 mmol/g	50g

B7.5.1.4.4 TentaGel® S RAM RAM Linker Attached to Standard TentaGel Resins
Standard resin for a large number of applications, useful in batch and flow through systems. This resin is recommended for synthesis of standard peptide amides up to 40 residues in length.
This resin is functionalized with a modified Rink Amide linker and is ideal for the Fmoc SPPS of peptide amides. Cleavage from this support is achieved by 95 % TFA.

貨號	名稱	particle size	capacity	包裝
S 30 023	TentaGel® S RAM	90 µm	0.2 - 0.27 mmol/g	1g
S 30 023	TentaGel® S RAM	90 µm	0.2 - 0.27 mmol/g	5g
S 30 023	TentaGel® S RAM	90 µm	0.2 - 0.27 mmol/g	25g
S 30 023	TentaGel® S RAM	90 µm	0.2 - 0.27 mmol/g	100g

B7.5.2 Resins for Carboxy Terminated Compounds
B7.5.2.1 3-Methoxy-4-(Hydroxymethyl) Phenoxyacetic Acid Based Resins (AC-Linker) on TentaGel®
B7.5.2.1.1 TentaGel® HL AC AC Linker on High Loaded TentaGel Resins

貨號	名稱	particle size	capacity	包裝
HL 12 011	TentaGel® HL AC	75 µm	0.3 - 0.4 mmol/g	1g
HL 12 011	TentaGel® HL AC	75 µm	0.3 - 0.4 mmol/g	5g
HL 12 011	TentaGel® HL AC	75 µm	0.3 - 0.4 mmol/g	25g
HL 12 011	TentaGel® HL AC	75 µm	0.3 - 0.4 mmol/g	50g

B7.5.2.1.2 TentaGel® MB AC AC Linker on TentaGel Macrobead Resins

貨號	名稱	particle size	capacity	包裝
MB 160 110	TentaGel® MB AC	140 - 170 µm	0.4 - 0.6 mmol/g	1g
MB 160 110	TentaGel® MB AC	140 - 170 µm	0.4 - 0.6 mmol/g	5g
MB 160 110	TentaGel® MB AC	140 - 170 µm	0.4 - 0.6 mmol/g	25g
MB 160 110	TentaGel® MB AC	140 - 170 µm	0.4 - 0.6 mmol/g	50g
MB 250 110	TentaGel® MB AC	200 - 250 µm	0.2 - 0.3 mmol/g	1g
MB 250 110	TentaGel® MB AC	200 - 250 µm	0.2 - 0.3 mmol/g	5g
MB 250 110	TentaGel® MB AC	200 - 250 µm	0.2 - 0.3 mmol/g	25g
MB 250 110	TentaGel® MB AC	200 - 250 µm	0.2 - 0.3 mmol/g	50g
MB 300 110	TentaGel® MB AC	280 - 320 µm	0.2 - 0.3 mmol/g	1g
MB 300 110	TentaGel® MB AC	280 - 320 µm	0.2 - 0.3 mmol/g	5g
MB 300 110	TentaGel® MB AC	280 - 320 µm	0.2 - 0.3 mmol/g	25g
MB 300 110	TentaGel® MB AC	280 - 320 µm	0.2 - 0.3 mmol/g	50g

B7.5.2.1.3 TentaGel® S AC AC Linker on Standard TentaGel Resins
Standard resin for a large number of applications, useful in batch and flow through systems.
Esters can be cleaved by 1-5% TFA in CH?Cl?.

貨號	名稱	particle size	capacity	包裝
S 30 011	TentaGel® S AC	90 µm	0.2 - 0.3 mmol/g	1g
S 30 011	TentaGel® S AC	90 µm	0.2 - 0.3 mmol/g	5g
S 30 011	TentaGel® S AC	90 µm	0.2 - 0.3 mmol/g	25g
S 30 011	TentaGel® S AC	90 µm	0.2 - 0.3 mmol/g	50g

B7.5.2.2 HMPA Polystyrene Resins
B7.5.2.2.1 4-(Hydroxymethyl) Phenoxyacetic Acid (HMPA) on Aminoethyl Polystyrene Resins

貨號	名稱	particle size	capacity	包裝
HA 1 100 15	Polystyrene A HMPA	100 - 200 mesh	0.8 - 1.2 mmol/g	5g
HA 1 100 15	Polystyrene A HMPA	100 - 200 mesh	0.8 - 1.2 mmol/g	25g
HA 1 100 15	Polystyrene A HMPA	100 - 200 mesh	0.8 - 1.2 mmol/g	100g
HA 1 400 15	Polystyrene A HMPA	200 - 400 mesh	0.8 - 1.2 mmol/g	5g
HA 1 400 15	Polystyrene A HMPA	200 - 400 mesh	0.8 - 1.2 mmol/g	25g
HA 1 400 15	Polystyrene A HMPA	200 - 400 mesh	0.8 - 1.2 mmol/g	100g
HA 125160 15	Polystyrene A HMPA	125 - 160 µm	0.8 - 1.2 mmol/g	5g
HA 125160 15	Polystyrene A HMPA	125 - 160 µm	0.8 - 1.2 mmol/g	25g
HA 125160 15	Polystyrene A HMPA	125 - 160 µm	0.8 - 1.2 mmol/g	100g
HA 160200 15	Polystyrene A HMPA	160 - 200 µm	0.8 - 1.2 mmol/g	5g
HA 160200 15	Polystyrene A HMPA	160 - 200 µm	0.8 - 1.2 mmol/g	25g
HA 160200 15	Polystyrene A HMPA	160 - 200 µm	0.8 - 1.2 mmol/g	100g
HA 250315 15	Polystyrene A HMPA	250 - 315 µm	0.6 - 1.0 mmol/g	5g
HA 250315 15	Polystyrene A HMPA	250 - 315 µm	0.6 - 1.0 mmol/g	25g
HA 250315 15	Polystyrene A HMPA	250 - 315 µm	0.6 - 1.0 mmol/g	100g
HA 400450 15	Polystyrene A HMPA	400 - 450 µm	0.6 - 1.0 mmol/g	5g
HA 400450 15	Polystyrene A HMPA	400 - 450 µm	0.6 - 1.0 mmol/g	25g
HA 400450 15	Polystyrene A HMPA	400 - 450 µm	0.6 - 1.0 mmol/g	100g
HA 500560 15	Polystyrene A HMPA	500 - 560 µm	0.6 - 1.0 mmol/g	5g
HA 500560 15	Polystyrene A HMPA	500 - 560 µm	0.6 - 1.0 mmol/g	25g
HA 500560 15	Polystyrene A HMPA	500 - 560 µm	0.6 - 1.0 mmol/g	100g

B7.5.2.2.2 4-(Hydroxymethyl) Phenoxyacetic Acid (HMPA) on Aminomethyl Polystyrene Resins
This resin is derivatized from aminomethyl polystyrene by coupling with the TFA-labile 4-(hydroxymethyl)-phenoxyacetic acid linker and is an alternative to the PHB resins.

貨號	名稱	particle size	capacity	包裝
H 100 15	Polystyrene AM HMPA	100 - 200 mesh	0.8 - 1.2 mmol/g	5g
H 100 15	Polystyrene AM HMPA	100 - 200 mesh	0.8 - 1.2 mmol/g	25g
H 100 15	Polystyrene AM HMPA	100 - 200 mesh	0.8 - 1.2 mmol/g	100g
H 400 15	Polystyrene AM HMPA	200 - 400 mesh	0.8 - 1.2 mmol/g	5g
H 400 15	Polystyrene AM HMPA	200 - 400 mesh	0.8 - 1.2 mmol/g	25g
H 400 15	Polystyrene AM HMPA	200 - 400 mesh	0.8 - 1.2 mmol/g	100g
H 125160 15	Polystyrene AM HMPA	125 - 160 µm	0.8 - 1.2 mmol/g	5g
H 125160 15	Polystyrene AM HMPA	125 - 160 µm	0.8 - 1.2 mmol/g	25g
H 125160 15	Polystyrene AM HMPA	125 - 160 µm	0.8 - 1.2 mmol/g	100g
H 160200 15	Polystyrene AM HMPA	160 - 200 µm	0.8 - 1.2 mmol/g	5g
H 160200 15	Polystyrene AM HMPA	160 - 200 µm	0.8 - 1.2 mmol/g	25g
H 160200 15	Polystyrene AM HMPA	160 - 200 µm	0.8 - 1.2 mmol/g	100g
H 250315 15	Polystyrene AM HMPA	250 - 315 µm	0.6 - 1.0 mmol/g	5g
H 250315 15	Polystyrene AM HMPA	250 - 315 µm	0.6 - 1.0 mmol/g	25g
H 250315 15	Polystyrene AM HMPA	250 - 315 µm	0.6 - 1.0 mmol/g	100g
H 400450 15	Polystyrene AM HMPA	400 - 450 µm	0.6 - 1.0 mmol/g	5g
H 400450 15	Polystyrene AM HMPA	400 - 450 µm	0.6 - 1.0 mmol/g	25g
H 400450 15	Polystyrene AM HMPA	400 - 450 µm	0.6 - 1.0 mmol/g	100g
H 500560 15	Polystyrene AM HMPA	500 - 560 µm	0.6 - 1.0 mmol/g	5g
H 500560 15	Polystyrene AM HMPA	500 - 560 µm	0.6 - 1.0 mmol/g	25g
H 500560 15	Polystyrene AM HMPA	500 - 560 µm	0.6 - 1.0 mmol/g	100g

B7.5.2.3 Para Hydroxybenzyl Alcohol ( PHB, Wang Linker) attached to TentaGel® Resins
B7.5.2.3.1 TentaGel® HL PHB PHB Attached to High Loaded TentaGel Resins

貨號	名稱	particle size	capacity	包裝
HL12 013	TentaGel® HL PHB	75 µm	0.3 - 0.4 mmol/g	1g
HL12 013	TentaGel® HL PHB	75 µm	0.3 - 0.4 mmol/g	5g
HL12 013	TentaGel® HL PHB	75 µm	0.3 - 0.4 mmol/g	25g

B7.5.2.3.2 TentaGel® MB PHB PHB Attached to TentaGel Macrobead Resins
TentaGel® Macrobeads are highlighted by extraordinary large particle diameters and high capacities based on the TentaGel® technology and designed for single bead synthesis and single bead analysis.

貨號	名稱	particle size	capacity	包裝
MB 160 130	TentaGel® MB PHB	140 - 170 µm	0.3 - 0.5 mmol/g	1g
MB 160 130	TentaGel® MB PHB	140 - 170 µm	0.3 - 0.5 mmol/g	5g
MB 160 130	TentaGel® MB PHB	140 - 170 µm	0.3 - 0.5 mmol/g	25g
MB 250 130	TentaGel® MB PHB	200 - 250 µm	0.2 - 0.3 mmol/g	1g
MB 250 130	TentaGel® MB PHB	200 - 250 µm	0.2 - 0.3 mmol/g	5g
MB 250 130	TentaGel® MB PHB	200 - 250 µm	0.2 - 0.3 mmol/g	25g
MB 300 130	TentaGel® MB PHB	280 - 320 µm	0.2 - 0.3 mmol/g	1g
MB 300 130	TentaGel® MB PHB	280 - 320 µm	0.2 - 0.3 mmol/g	5g
MB 300 130	TentaGel® MB PHB	280 - 320 µm	0.2 - 0.3 mmol/g	25g

B7.5.2.3.3 TentaGel® R PHB PHB Attached to TentaGel Research Resins
A special designed resin for research synthesis. Long peptide sequences (up to 100 residues), difficult sequences and PNA´s are synthesized on this support. The resin shows an increased swelling volume and a significant lower loading.

貨號	名稱	particle size	capacity	包裝
R 28 013	TentaGel® R PHB	90 µm	0.18 - 0.23 mmol/g	1g
R 28 013	TentaGel® R PHB	90 µm	0.18 - 0.23 mmol/g	5g
R 28 013	TentaGel® R PHB	90 µm	0.18 - 0.23 mmol/g	25g
R 28 013	TentaGel® R PHB	90 µm	0.18 - 0.23 mmol/g	50g

B7.5.2.3.4 TentaGel® S PHB PHB Attached to Standard TentaGel Resins
Standard resin for a large number of applications, useful in batch and flow through systems. This resin is recommended for synthesis of standard peptides up to 40 residues in length.

貨號	名稱	particle size	capacity	包裝
S 30 013	TentaGel® S PHB	90 µm	0.2 - 0.3 mmol/g	1g
S 30 013	TentaGel® S PHB	90 µm	0.2 - 0.3 mmol/g	5g
S 30 013	TentaGel® S PHB	90 µm	0.2 - 0.3 mmol/g	25g
S 30 013	TentaGel® S PHB	90 µm	0.2 - 0.3 mmol/g	100g

B7.5.2.4 Para Hydroxybenzyl Alcohol ( PHB, Wang Linker) on HypoGel® Resins
HypoGel® is a hydrophilic gel type resin which combines high capacities with good solvent compatibility. Glycol spacers with n = 5 or 10 EO units separate the reactive sites from the polystyrene matrix and modify the hydrophobic properties of the polystyrene backbone. Due to the spacer effect the functional group shows a higher mobility which results in higher kinetic rates and high resolution NMR spectra from immobilized compounds on the bead. The resin is compatible to a wide range of solvents and in contrast to polystyrene even polar solvents like methanol or ethanol can be used.
These resins show high capacities and a hydrophilicity between polystyrene and TentaGel®
The parahydroxybencyl alcohol attached to TentaGel make this resin ideal for attaching carboxylic acids for further functionalisation and peptide synthesis. Cleavage conditions are concentrated TFA or TFA/CH?CI? mixtures to provide carboxylic acids, peptides or cyclization-cleavage under acidic or basic conditions. This resin is recommended for the synthesis of short peptides (10 - 15 residues).
Literature
L 17

貨號	名稱	particle size	capacity	包裝
SP200 110150 130	HypoGel® 200 PHB	110 - 150 µm	0.6 - 0.8 mmol/g	5g
SP200 110150 130	HypoGel® 200 PHB	110 - 150 µm	0.6 - 0.8 mmol/g	25g
SP200 110150 130	HypoGel® 200 PHB	110 - 150 µm	0.6 - 0.8 mmol/g	100g
SP400 110150 130	HypoGel® 400 PHB	110 - 150 µm	0.4 - 0.6 mmol/g	5g
SP400 110150 130	HypoGel® 400 PHB	110 - 150 µm	0.4 - 0.6 mmol/g	25g
SP400 110150 130	HypoGel® 400 PHB	110 - 150 µm	0.4 - 0.6 mmol/g	100g

B7.5.2.5 Parahydroxybenzyl Alcohol Polystyrene Resins (PHB, Wang-type)
B7.5.2.5.1 Para Hydroxybenzyl Alcohol (PHB, Wang Linker ) on Ethylated Polystyrene Matrix

貨號	名稱	particle size	capacity	包裝
HA 1 100 13	Polystyrene A PHB	100 - 200 mesh	0.5 - 1.0 mmol/g	5g
HA 1 100 13	Polystyrene A PHB	100 - 200 mesh	0.5 - 1.0 mmol/g	25g
HA 1 100 13	Polystyrene A PHB	100 - 200 mesh	0.5 - 1.0 mmol/g	100g
HA 1 400 13	Polystyrene A PHB	200 - 400 mesh	0.5 - 1.0 mmol/g	5g
HA 1 400 13	Polystyrene A PHB	200 - 400 mesh	0.5 - 1.0 mmol/g	25g
HA 1 400 13	Polystyrene A PHB	200 - 400 mesh	0.5 - 1.0 mmol/g	100g
HA 125160 13	Polystyrene A PHB	125 - 160 µm	0.5 - 1.0 mmol/g	5g
HA 125160 13	Polystyrene A PHB	125 - 160 µm	0.5 - 1.0 mmol/g	25g
HA 125160 13	Polystyrene A PHB	125 - 160 µm	0.5 - 1.0 mmol/g	100g
HA 160200 13	Polystyrene A PHB	160 - 200 µm	0.5 - 0.8 mmol/g	5g
HA 160200 13	Polystyrene A PHB	160 - 200 µm	0.5 - 0.8 mmol/g	25g
HA 160200 13	Polystyrene A PHB	160 - 200 µm	0.5 - 0.8 mmol/g	100g
HA 250315 13	Polystyrene A PHB	250 - 315 µm	0.5 - 0.8 mmol/g	5g
HA 250315 13	Polystyrene A PHB	250 - 315 µm	0.5 - 0.8 mmol/g	25g
HA 250315 13	Polystyrene A PHB	250 - 315 µm	0.5 - 0.8 mmol/g	100g
HA 400450 13	Polystyrene A PHB	400 - 450 µm	0.5 - 0.8 mmol/g	5g
HA 400450 13	Polystyrene A PHB	400 - 450 µm	0.5 - 0.8 mmol/g	25g
HA 400450 13	Polystyrene A PHB	400 - 450 µm	0.5 - 0.8 mmol/g	100g
HA 500560 13	Polystyrene A PHB	500 - 560 µm	0.5 - 0.8 mmol/g	5g
HA 500560 13	Polystyrene A PHB	500 - 560 µm	0.5 - 0.8 mmol/g	25g
HA 500560 13	Polystyrene A PHB	500 - 560 µm	0.5 - 0.8 mmol/g	100g

B7.5.2.5.2 Para Hydroxybenzyl Alcohol (PHB, Wang Linker) on Butylated Polystyrene Matrix
The linker is separated by a C4 spacer from the crosslinked matrix. Due to this spacer effect the functional group shows a higher mobility which results in higher kinetic rates and high resolution NMR spectra from immobilized compounds on the bead.

貨號	名稱	particle size	capacity	包裝
HB 045080 13	Polystyrene C4 PHB	45 - 80 µm	0.8 - 1.2 mmol/g	5g
HB 045080 13	Polystyrene C4 PHB	45 - 80 µm	0.8 - 1.2 mmol/g	25g
HB 045080 13	Polystyrene C4 PHB	45 - 80 µm	0.8 - 1.2 mmol/g	100g
HB 080160 13	Polystyrene C4 PHB	80 - 160 µm	0.8 - 1.2 mmol/g	5g
HB 080160 13	Polystyrene C4 PHB	80 - 160 µm	0.8 - 1.2 mmol/g	25g
HB 080160 13	Polystyrene C4 PHB	80 - 160 µm	0.8 - 1.2 mmol/g	100g
HB 125160 13	Polystyrene C4 PHB	125 - 160 µm	0.8 - 1.2 mmol/g	5g
HB 125160 13	Polystyrene C4 PHB	125 - 160 µm	0.8 - 1.2 mmol/g	25g
HB 125160 13	Polystyrene C4 PHB	125 - 160 µm	0.8 - 1.2 mmol/g	100g

B7.5.2.5.3 Wang Resin - Para Hydroxybenzyl Alcohol (PHB) on Polystyrene
The Wang support is the most widely used resin for attaching carboxylic acids for further functionalisation. Cleavage conditions for the ester anchor involve concentrated TFA or TFA/CH?CI? mixtures to provide carboxylic acids or cyclization-cleavage under acidic or basic conditions. Release of an amide function by treatment with an amine in the presence of a Lewis acid was also reported. Wang resin was used to add vinyl and iodobenzoic acids via carbodiimide coupling and the products subjected to Heck conditions with alkenes or with alkynes or to Suzuki coupling with boron reagents. The Ugi multicomponent condensation reaction was conducted on Wang resin with the carboxylic acid, amine or isonitrile as the anchored functional group. On a Wang resin primary, secondary, and tertiary alcohols have been converted to 4-methoxy-benzyl ethers. As well as anchoring carboxylic acids to this resin, phenols were attached under Mitsunobu conditions, subjected to further transformations and cleaved under acidic conditions.
Solid-phase lactam syntheses were also achieved by reaction of the resin-bound isonitrile with an amine and an w-keto-acid as well as other synthetic transformations such as the Biginelli reaction and construction of heterocycles such as quinolones, imidazoles, hydantoins, and 1,4-benzodiazepine-2,5-diones.
Literature
L 39

貨號	名稱	particle size	capacity	包裝
H 100 13	Polystyrene PHB (Wang resin)	100 - 200 mesh	0.8 - 1.25 mmol/g	5g
H 100 13	Polystyrene PHB (Wang resin)	100 - 200 mesh	0.8 - 1.25 mmol/g	25g
H 100 13	Polystyrene PHB (Wang resin)	100 - 200 mesh	0.8 - 1.25 mmol/g	100g
H 400 13	Polystyrene PHB (Wang resin)	200 - 400 mesh	0.8 - 1.25 mmol/g	5g
H 400 13	Polystyrene PHB (Wang resin)	200 - 400 mesh	0.8 - 1.25 mmol/g	25g
H 400 13	Polystyrene PHB (Wang resin)	200 - 400 mesh	0.8 - 1.25 mmol/g	100g
H 125160 13	Polystyrene PHB (Wang resin)	125 - 160 µm	0.8 - 1.25 mmol/g	5g
H 125160 13	Polystyrene PHB (Wang resin)	125 - 160 µm	0.8 - 1.25 mmol/g	25g
H 125160 13	Polystyrene PHB (Wang resin)	125 - 160 µm	0.8 - 1.25 mmol/g	100g

B7.5.3 Resins for Protected Peptide Amides
TOPPA - A Novel Resin for Synthesis of Protected Peptide Amides
This resin type is based on a TentaGel or polystyrene matrix and combines the very acid sensitive trityl handle with the acid sensitive Rink amide handle. The peptide synthesis can be performed by standard conditions. Treatment of the TOPPA resin with diluted AcOH, TFE or mixtures of both in dichloromethane cleaves the trityl ester bond and releases the total protected peptide amide (TOPPA). The C-terminus of the protected peptide amide is still masked by the Rink handle.
Literature
L 50
Please select a subcategory:
B7.5.3.1 Protected Amides from Polystyrene Resins

貨號	名稱	particle size	capacity	包裝
H 75150.033023	PS TOPPA	75 - 150 µm	0.6 - 0.9 mmol/g	1g
H 75150.033023	PS TOPPA	75 - 150 µm	0.6 - 0.9 mmol/g	5g
H 75150.033023	PS TOPPA	75 - 150 µm	0.6 - 0.9 mmol/g	25g

B7.5.3.2 Protected Amides from TentaGel Resins

貨號	名稱	particle size	capacity	包裝
S 30902.012023	TentaGel® TOPPA	90 µm	0.18 - 0.25 mmol/g	1g
S 30902.012023	TentaGel® TOPPA	90 µm	0.18 - 0.25 mmol/g	5g
S 30902.012023	TentaGel® TOPPA	90 µm	0.18 - 0.25 mmol/g	25g

B7.5.4 Resins for the Synthesis of Thioesters
Trityl Mercapto Acetyl Leu PAM loaded to Aminomethyl Polystyrene
This resin can be used for the synthesis of peptide thioesters by Boc chemistry. After removal of the trityl protecting group by TFA/DCM treatment the first Boc amino acid is loaded to the resin by DIC/HOBt activation. Peptide synthesis follows the standard Boc synthesis protocol.
After finishing the peptide synthesis, the peptide thioester resin is treated by HF resulting in the deprotected peptide thioester derivative which can be used for native chemical ligation.
Literature
L 55

貨號	名稱	particle size	capacity	包裝
H 100 90	Polystyrene AM PAM Leu Acetyl Mercapto Trt	100 - 200 mesh	0.6 - 0.9 mmol/g	1g
H 100 90	Polystyrene AM PAM Leu Acetyl Mercapto Trt	100 - 200 mesh	0.6 - 0.9 mmol/g	5g

B7.5.5 Trityl Based Linkers
B7.5.5.1 Chloro-(2'-chloro)trityl Polystyrene Resins
A very acid sensitive resin suitable for the synthesis of protected peptide fragments by the Fmoc-strategy. In particular suitable for the preparation of C-terminal prolyl and cysteinyl peptides. Cleavage from this resin is achieved by using 1-95% TFA in CH?CI? (containing 8% triisopropylsilane), AcOH/CF?OH/CH?CI?, 0.5% TFA or hexafluoroisopropanol. Recently, this resin has been used in cyclization reactions under Heck reaction conditions, the solid phase synthesis of b-peptides via the Arndt-Eistert homologation of Fmoc-protected amino acid diazoketones and in Mannich reactions of alkynes, secondary amines and aldehydes in the presence of a copper (I) salt affording the corresponding aminomethylalkynyl adducts.
This resin can also be used in Fmoc peptide synthesis. Carboxylic acids can be released under very mild acidic conditions by treatment with AcOH/TFE/DCM or HFIP in DCM. Completely protected peptides are generated under this condition.
Literature
L 37

貨號	名稱	particle size	capacity	包裝
H 100 33	Chloro-(2'-chloro)trityl Polystyrene	100 - 200 mesh	0.8 - 1.5 mmol/g	5g
H 100 33	Chloro-(2'-chloro)trityl Polystyrene	100 - 200 mesh	0.8 - 1.5 mmol/g	25g
H 100 33	Chloro-(2'-chloro)trityl Polystyrene	100 - 200 mesh	0.8 - 1.5 mmol/g	100g
H 400 33	Chloro-(2'-chloro)trityl Polystyrene	200 - 400 mesh	0.8 - 1.5 mmol/g	5g
H 400 33	Chloro-(2'-chloro)trityl Polystyrene	200 - 400 mesh	0.8 - 1.5 mmol/g	25g
H 400 33	Chloro-(2'-chloro)trityl Polystyrene	200 - 400 mesh	0.8 - 1.5 mmol/g	100g
H 125160 33	Chloro-(2'-chloro)trityl Polystyrene	125 - 160 µm	0.8 - 1.5 mmol/g	5g
H 125160 33	Chloro-(2'-chloro)trityl Polystyrene	125 - 160 µm	0.8 - 1.5 mmol/g	25g
H 125160 33	Chloro-(2'-chloro)trityl Polystyrene	125 - 160 µm	0.8 - 1.5 mmol/g	100g
H 160200 33	Chloro-(2'-chloro)trityl Polystyrene	160 - 200 µm	0.8 - 1.3 mmol/g	5g
H 160200 33	Chloro-(2'-chloro)trityl Polystyrene	160 - 200 µm	0.8 - 1.3 mmol/g	25g
H 160200 33	Chloro-(2'-chloro)trityl Polystyrene	160 - 200 µm	0.8 - 1.3 mmol/g	100g
H 250315 33	Chloro-(2'-chloro)trityl Polystyrene	250 - 315 µm	0.6 - 1.0 mmol/g	5g
H 250315 33	Chloro-(2'-chloro)trityl Polystyrene	250 - 315 µm	0.6 - 1.0 mmol/g	25g
H 250315 33	Chloro-(2'-chloro)trityl Polystyrene	250 - 315 µm	0.6 - 1.0 mmol/g	100g
H 400450 33	Chloro-(2'-chloro)trityl Polystyrene	400 - 450 µm	0.6 - 1.0 mmol/g	5g
H 400450 33	Chloro-(2'-chloro)trityl Polystyrene	400 - 450 µm	0.6 - 1.0 mmol/g	25g
H 400450 33	Chloro-(2'-chloro)trityl Polystyrene	400 - 450 µm	0.6 - 1.0 mmol/g	100g
H 500560 33	Chloro-(2'-chloro)trityl Polystyrene	500 - 560 µm	0.6 - 1.0 mmol/g	5g
H 500560 33	Chloro-(2'-chloro)trityl Polystyrene	500 - 560 µm	0.6 - 1.0 mmol/g	25g
H 500560 33	Chloro-(2'-chloro)trityl Polystyrene	500 - 560 µm	0.6 - 1.0 mmol/g	100g

B7.5.5.2 Chlorotrityl Polystyrene Resins (Trityl Chloride Resin)
This highly acid labile resin is useful for the immobilization of alcohols, amines and carboxylic acids. Cleavage is in general achieved by using either 1-5 % TFA in CH?Cl? (containing 5 % triisopropylsilane) or acetic acid.
This resin can also be used in Fmoc peptide synthesis under basic acylation conditions. Carboxylic acids can be released under very mild acidic conditions by treatment with AcOH/TFE/DCM or HFIP in DCM. Completely protected peptides are generated under this conditions.
Literature
L 36

貨號	名稱	particle size	capacity	包裝
H 100 31	Chlorotrityl Polystyrene	100 - 200 mesh	0.8 - 1.5 mmol/g	5g
H 100 31	Chlorotrityl Polystyrene	100 - 200 mesh	0.8 - 1.5 mmol/g	25g
H 100 31	Chlorotrityl Polystyrene	100 - 200 mesh	0.8 - 1.5 mmol/g	100g
H 400 31	Chlorotrityl Polystyrene	200 - 400 mesh	0.8 - 1.5 mmol/g	5g
H 400 31	Chlorotrityl Polystyrene	200 - 400 mesh	0.8 - 1.5 mmol/g	25g
H 400 31	Chlorotrityl Polystyrene	200 - 400 mesh	0.8 - 1.5 mmol/g	100g
H 125160 31	Chlorotrityl Polystyrene	125 - 160 µm	0.8 - 1.5 mmol/g	5g
H 125160 31	Chlorotrityl Polystyrene	125 - 160 µm	0.8 - 1.5 mmol/g	25g
H 125160 31	Chlorotrityl Polystyrene	125 - 160 µm	0.8 - 1.5 mmol/g	100g
H 160200 31	Chlorotrityl Polystyrene	160 - 200 µm	0.8 - 1.3 mmol/g	5g
H 160200 31	Chlorotrityl Polystyrene	160 - 200 µm	0.8 - 1.3 mmol/g	25g
H 160200 31	Chlorotrityl Polystyrene	160 - 200 µm	0.8 - 1.3 mmol/g	100g
H 250315 31	Chlorotrityl Polystyrene	250 - 315 µm	0.6 - 1.0 mmol/g	5g
H 250315 31	Chlorotrityl Polystyrene	250 - 315 µm	0.6 - 1.0 mmol/g	25g
H 250315 31	Chlorotrityl Polystyrene	250 - 315 µm	0.6 - 1.0 mmol/g	100g
H 400450 31	Chlorotrityl Polystyrene	400 - 450 µm	0.6 - 1.0 mmol/g	5g
H 400450 31	Chlorotrityl Polystyrene	400 - 450 µm	0.6 - 1.0 mmol/g	25g
H 400450 31	Chlorotrityl Polystyrene	400 - 450 µm	0.6 - 1.0 mmol/g	100g
H 500560 31	Chlorotrityl Polystyrene	500 - 560 µm	0.6 - 1.0 mmol/g	5g
H 500560 31	Chlorotrityl Polystyrene	500 - 560 µm	0.6 - 1.0 mmol/g	25g
H 500560 31	Chlorotrityl Polystyrene	500 - 560 µm	0.6 - 1.0 mmol/g	100g

B7.5.5.3 Hydroxytrityl Polystyrene Resins

貨號	名稱	particle size	capacity	包裝
H 100 30	Hydroxytrityl Polystyrene	100 - 200 mesh	0.8 - 1.5 mmol/g	5g
H 100 30	Hydroxytrityl Polystyrene	100 - 200 mesh	0.8 - 1.5 mmol/g	25g
H 100 30	Hydroxytrityl Polystyrene	100 - 200 mesh	0.8 - 1.5 mmol/g	100g
H 400 30	Hydroxytrityl Polystyrene	200 - 400 mesh	0.8 - 1.5 mmol/g	5g
H 400 30	Hydroxytrityl Polystyrene	200 - 400 mesh	0.8 - 1.5 mmol/g	25g
H 400 30	Hydroxytrityl Polystyrene	200 - 400 mesh	0.8 - 1.5 mmol/g	100g
H 125160 30	Hydroxytrityl Polystyrene	125 - 160 µm	0.8 - 1.5 mmol/g	5g
H 125160 30	Hydroxytrityl Polystyrene	125 - 160 µm	0.8 - 1.5 mmol/g	25g
H 125160 30	Hydroxytrityl Polystyrene	125 - 160 µm	0.8 - 1.5 mmol/g	100g
H 160200 30	Hydroxytrityl Polystyrene	160 - 200 µm	0.8 - 1.3 mmol/g	5g
H 160200 30	Hydroxytrityl Polystyrene	160 - 200 µm	0.8 - 1.3 mmol/g	25g
H 160200 30	Hydroxytrityl Polystyrene	160 - 200 µm	0.8 - 1.3 mmol/g	100g
H 250315 30	Hydroxytrityl Polystyrene	250 - 315 µm	0.6 - 1.0 mmol/g	5g
H 250315 30	Hydroxytrityl Polystyrene	250 - 315 µm	0.6 - 1.0 mmol/g	25g
H 250315 30	Hydroxytrityl Polystyrene	250 - 315 µm	0.6 - 1.0 mmol/g	100g
H 400450 30	Hydroxytrityl Polystyrene	400 - 450 µm	0.6 - 1.0 mmol/g	5g
H 400450 30	Hydroxytrityl Polystyrene	400 - 450 µm	0.6 - 1.0 mmol/g	25g
H 400450 30	Hydroxytrityl Polystyrene	400 - 450 µm	0.6 - 1.0 mmol/g	100g
H 500560 30	Hydroxytrityl Polystyrene	500 - 560 µm	0.6 - 1.0 mmol/g	5g
H 500560 30	Hydroxytrityl Polystyrene	500 - 560 µm	0.6 - 1.0 mmol/g	25g
H 500560 30	Hydroxytrityl Polystyrene	500 - 560 µm	0.6 - 1.0 mmol/g	100g

B7.5.5.4 Trityl Linker on Polar PEG Spacer Resins
B7.5.5.4.1 HypoGel® Resins with Trityl Linker
HypoGel® is a hydrophilic gel type resin which combines high capacities with good solvent compatibility. Glycol spacers with n = 5 or 10 EO units separate the reactive sites from the polystyrene matrix and modify the hydrophobic properties of the polystyrene backbone. The hydrophilicity is between polystyrene and TentaGel® . Due to the spacer effect the functional group shows a higher mobility which results in higher kinetic rates and high resolution NMR spectra from immobilized compounds on the bead. The resin is compatible to a wide range of solvents and in contrast to polystyrene even polar solvents like methanol or ethanol can be used.
HypoGel® is a registered Trademark of Rapp Polymere GmbH
Literature: L 17
This very acid sensitive linker is useful for the immobilization of alcohols, amines and carboxylic acids. Before use, the trityl alcohol must be converted to the trityl chloride by treatment with acetyl chloride in DCM. The sensitivity towards acids is very comparable to the 2-chlorotrityl linker. Cleavage is in general achieved by using either 5 - 50 % TFA in CH?Cl? (containing 5 % triisopropylsilane) or acetic acid.
This resin can also be used in Fmoc peptide synthesis. Carboxylic acids can be released under very mild acidic conditions by treatment with AcOH/TFE/DCM or HFIP in DCM. Completely protected peptides are generated under this conditions.
Residues which are sensitive to racemisation during esterification reactions like His and Cys can be attached to the resin without racemisation. Due to the bulkiness of the trityl group, diketopiperazine formation is suppressed which make this linker ideal for peptides with C-terminal Pro.

貨號	名稱	particle size	capacity	包裝
SP200 110150 120	HypoGel® 200 TRT-OH	110 - 150 µm	0.6 - 0.8 mmol/g	5g
SP200 110150 120	HypoGel® 200 TRT-OH	110 - 150 µm	0.6 - 0.8 mmol/g	25g
SP200 110150 120	HypoGel® 200 TRT-OH	110 - 150 µm	0.6 - 0.8 mmol/g	100g
SP400 110150 120	HypoGel® 400 TRT-OH	110 - 150 µm	0.4 - 0.6 mmol/g	5g
SP400 110150 120	HypoGel® 400 TRT-OH	110 - 150 µm	0.4 - 0.6 mmol/g	25g
SP400 110150 120	HypoGel® 400 TRT-OH	110 - 150 µm	0.4 - 0.6 mmol/g	100g

B7.5.5.4.2 TentaGel® Resins with Trityl Linker
TentaGel® resins are grafted copolymers consisting of a low crosslinked polystyrene matrix on which polyethylene glycol (PEG or POE) is grafted. The PEG spacer is attached to the matrix via an ethyl ether group which increases stability towards acid treatment and minimizes PEG-leaching. As PEG is a "chameleon type" polymer with hydrophobic and hydrophilic properties, the graft copolymer shows modified physico chemical properties which are highly dominated by the PEG moiety (and no longer by the polystyrene matrix). These graft copolymers are pressure stable and can be used in batch processes as well as under continuous flow conditions. The PEG spacer is in the range of MW 3000 Da.
This highly acid sensitive linker is useful for the immobilization of alcohols, amines and carboxylic acids. Before use, the trityl alcohol must be converted to the trityl chloride by treatment with acetyl chloride in DCM. The sensitivity towards acids is very comparable to the 2-chlorotrityl linker. Cleavage is in general achieved by using either 5 - 50 % TFA in CH?Cl? (containing 5 % triisopropylsilane) or acetic acid.
This resin can also be used in Fmoc peptide synthesis. Carboxylic acids can be released under very mild acidic conditions by treatment with AcOH/TFE/DCM or HFIP in DCM. Completely protected peptides are generated under this conditions.
Residues which are sensitive to racemisation during esterification reactions like His and Cys can be attached to the resin without racemisation. Due to the bulkiness of the trityl group, diketopiperazine formation is suppressed which makes this linker ideal for peptides with C-terminal Pro.
Literature
L 4, L 5, L 6, L 7, L 24, L 25; see also: General Information
B7.5.5.4.2.1 TentaGel® HL TRT High Loaded TentaGel Resins with Hydroxytrityl Linker
This high loaded version of TentaGel® combines a significantly higher capacity with the advantages of
TentaGel® resins. The spacer is in the range of MW 1500 - 2000 Da.

貨號	名稱	particle size	capacity	包裝
HL12 012	TentaGel® HL TRT-OH	75 µm	0.3 - 0.4 mmol/g	1g
HL12 012	TentaGel® HL TRT-OH	75 µm	0.3 - 0.4 mmol/g	5g
HL12 012	TentaGel® HL TRT-OH	75 µm	0.3 - 0.4 mmol/g	25g
HL12 012	TentaGel® HL TRT-OH	75 µm	0.3 - 0.4 mmol/g	50g

B7.5.5.4.2.2 TentaGel® MB TRT TentaGel Macrobead Resins with Hydroxytrityl Linker
TentaGel® Macrobeads are highlighted by extraordinary large particle diameters and high capacities based on the TentaGel® technology and designed for single bead synthesis and single bead analysis.

貨號	名稱	particle size	capacity	包裝
MB 160 120	TentaGel® MB TRT-OH	140 - 170 µm	0.4 - 0.5 mmol/g	1g
MB 160 120	TentaGel® MB TRT-OH	140 - 170 µm	0.4 - 0.5 mmol/g	5g
MB 160 120	TentaGel® MB TRT-OH	140 - 170 µm	0.4 - 0.5 mmol/g	25g
MB 160 120	TentaGel® MB TRT-OH	140 - 170 µm	0.4 - 0.5 mmol/g	50g
MB 250 120	TentaGel® MB TRT-OH	200 - 250 µm	0.2 - 0.3 mmol/g	1g
MB 250 120	TentaGel® MB TRT-OH	200 - 250 µm	0.2 - 0.3 mmol/g	5g
MB 250 120	TentaGel® MB TRT-OH	200 - 250 µm	0.2 - 0.3 mmol/g	25g
MB 250 120	TentaGel® MB TRT-OH	200 - 250 µm	0.2 - 0.3 mmol/g	50g
MB 300 120	TentaGel® MB TRT-OH	280 - 320 µm	0.2 - 0.3 mmol/g	1g
MB 300 120	TentaGel® MB TRT-OH	280 - 320 µm	0.2 - 0.3 mmol/g	5g
MB 300 120	TentaGel® MB TRT-OH	280 - 320 µm	0.2 - 0.3 mmol/g	25g
MB 300 120	TentaGel® MB TRT-OH	280 - 320 µm	0.2 - 0.3 mmol/g	50g

B7.5.5.4.2.3 TentaGel® R TRT Cl TentaGel Research Resins with Chlorotrityl Linker
TentaGel® R TRT Cl TentaGel Research Resins with Chlorotrityl Linker
This preactivated resin is ready for loading with nucleophilic compounds and amino acids under basic conditions. Due to the hygroscopic nature of TentaGel resins, the resin should be used immediately.
A special designed resin for research synthesis. This resin is recommended for long peptide sequences (up to 100 residues) and difficult sequences. The resin shows an increased swelling volume and a significant lower loading.
This highly acid sensitive linker is useful for the immobilization of alcohols, amines and carboxylic acids. The sensitivity towards acids is very comparable to the 2-chlorotrityl linker. Cleavage is in general achieved by using either 5 - 50 % TFA in CH?Cl? (containing 5 % triisopropylsilane) or acetic acid.
This resin can also be used in Fmoc peptide synthesis. Carboxylic acids can be released under very mild acidic conditions by treatment with AcOH/TFE/DCM or HFIP in DCM. Completely protected peptides are generated under this conditions. The sensitivity toward acid treatment is comparable to the 2-CTC linker.
Residues which are sensitive to racemisation during esterification reactions like His and Cys can be attached to the resin without racemisation. Due to the bulkiness of the trityl group, diketopiperazine formation is suppressed which make this linker ideal for peptides with C-terminal Pro.

貨號	名稱	particle size	capacity	包裝
R 28 031	TentaGel® R TRT-Cl	90 µm	0.15 - 0.22 mmol/g	5g
R 28 031	TentaGel® R TRT-Cl	90 µm	0.15 - 0.22 mmol/g	25g
R 28 031	TentaGel® R TRT-Cl	90 µm	0.15 - 0.22 mmol/g	50g

B7.5.5.4.2.4 TentaGel® S TRT Standard TentaGel Resins with Hydroxytrityl Linker
Standard resin for a large number of applications, useful in batch and flow through systems.

貨號	名稱	particle size	capacity	包裝
S 30 012	TentaGel® S TRT-OH	90 µm	0.2 - 0.28 mmol/g	1g
S 30 012	TentaGel® S TRT-OH	90 µm	0.2 - 0.28 mmol/g	5g
S 30 012	TentaGel® S TRT-OH	90 µm	0.2 - 0.28 mmol/g	25g
S 30 012	TentaGel® S TRT-OH	90 µm	0.2 - 0.28 mmol/g	50g

B7.5.5.4.2.5 TentaGel® S TRT Cl Standard TentaGel Resins with Chlorotrityl Linker
TentaGel® S TRT Cl Standard TentaGel Resins with Chlorotrityl Linker
This preactivated resin is ready for loading with nucleophilic compounds and amino acids under basic conditions. Due to the hygroscopic nature of TentaGel resins, the resin should be used immediately.
Standard resin for a large number of applications, useful in batch and flow through systems.
This resin is recommended for synthesis of standard peptides up to 40 residues in length.
This highly acid sensitive linker is useful for the immobilization of alcohols, amines and carboxylic acids. The sensitivity towards acids is very comparable to the 2-chlorotrityl linker. Cleavage is in general achieved by using either 5 - 50 % TFA in CH?Cl? (containing 5 % triisopropylsilane) or acetic acid.
This resin can also be used in Fmoc peptide synthesis. Carboxylic acids can be released under very mild acidic conditions by treatment with AcOH/TFE/DCM or HFIP in DCM. Completely protected peptides are generated under this conditions.
Residues which are sensitive to racemisation during esterification reactions like His and Cys can be attached to the resin without racemisation. Due to the bulkiness of the trityl group, diketopiperazine formation is suppressed which makes this linker ideal for peptides with C-terminal Pro.
Literature
L 14

貨號	名稱	particle size	capacity	包裝
S 30 031	TentaGel® S TRT-Cl	90 µm	0.2 - 0.3 mmol/g	5g
S 30 031	TentaGel® S TRT-Cl	90 µm	0.2 - 0.3 mmol/g	25g
S 30 031	TentaGel® S TRT-Cl	90 µm	0.2 - 0.3 mmol/g	50g

B7.6 Resins with Aromatic Formyl Linkers

B7.6.1 Polar PEG Spacer Resins with Aromatic Formyl Linker
B7.6.1.1 4-Formyl Phenoxy on HypoGel Resins ( FP-linker)
4-Formyl Phenoxy on HypoGel Resins ( FP-linker)
HypoGel® is a hydrophilic gel type resin which combines high capacities with good solvent compatibility. Glycol spacers with n = 5 or 10 EO units separate the reactive sites from the polystyrene matrix and modify the hydrophobic properties of the polystyrene backbone. Due to the spacer effect the functional group shows a higher mobility which results in higher kinetic rates and high resolution NMR spectra from immobilized compounds on the bead. The resin is compatible to a wide range of solvents and in contrast to polystyrene even polar solvents like methanol or ethanol can be used.
These resins show high loading and a hydrophilicity between polystyrene and TentaGel®
L 30, L 31
 
Due to the lack of amide bonds and of benzylic linkages as well as the very good swelling properties in a broad variety of solvents this resin is well suited for solid phase syntheses of secondary sulfonamides and carboxamides.
Literature
L17

貨號	名稱	particle size	capacity	包裝
SP200 110150 170	HypoGel® 200 FP	110 - 150 µm	0.5 - 0.7 mmol/g	5g
SP200 110150 170	HypoGel® 200 FP	110 - 150 µm	0.5 - 0.7 mmol/g	25g
SP200 110150 170	HypoGel® 200 FP	110 - 150 µm	0.5 - 0.7 mmol/g	100g
SP400 110150 170	HypoGel® 400 FP	110 - 150 µm	0.4 - 0.6 mmol/g	5g
SP400 110150 170	HypoGel® 400 FP	110 - 150 µm	0.4 - 0.6 mmol/g	25g
SP400 110150 170	HypoGel® 400 FP	110 - 150 µm	0.4 - 0.6 mmol/g	100g

B7.6.1.2 4-Formyl-3-Methoxy Phenoxy on HypoGel Resins ( FMP-linker)

貨號	名稱	particle size	capacity	包裝
SP200 110150 160	HypoGel® 200 FMP	110 - 150 µm	0.5 - 0.7 mmol/g	5g
SP200 110150 160	HypoGel® 200 FMP	110 - 150 µm	0.5 - 0.7 mmol/g	25g
SP200 110150 160	HypoGel® 200 FMP	110 - 150 µm	0.5 - 0.7 mmol/g	100g
SP400 110150 160	HypoGel® 400 FMP	110 - 150 µm	0.4 - 0.6 mmol/g	5g
SP400 110150 160	HypoGel® 400 FMP	110 - 150 µm	0.4 - 0.6 mmol/g	25g
SP400 110150 160	HypoGel® 400 FMP	110 - 150 µm	0.4 - 0.6 mmol/g	100g

B7.6.1.3 4-Formyl-3-Methoxy Phenoxy on TentaGel Resins ( FMP-linker)
4-Formyl-3-Methoxy Phenoxy on TentaGel Resins ( FMP-linker)
TentaGel® resins are grafted copolymers consisting of a low crosslinked polystyrene matrix on which polyethylene glycol (PEG or POE) is grafted. The PEG spacer is attached to the matrix via an ethyl ether group which increases stability towards acid treatment and minimizes PEG-leaching. As PEG is a "chameleon type" polymer with hydrophobic and hydrophilic properties, the graft copolymer shows modified physico chemical properties which are highly dominated by the PEG moiety (and no longer by the polystyrene matrix). These graft copolymers are pressure stable and can be used in batch processes as well as under continuous flow conditions. The PEG spacer is in the range of MW 3000 Da.
Due to the lack of amide bonds and of benzylic linkages as well as the excellent swelling properties in a great variety of solvents this resin is ideal for solid phase syntheses of secondary sulfonamides and carboxamides.
Literature
L 4, L 5, L 6, L 7, L 24, L 25, L 31; see also: General Information
B7.6.1.3.1 TentaGel® HL FMP High Loaded TentaGel Resins Modified with FMP Linker
This highloaded version of TentaGel® combines a significantly higher capacity with the advantages of TentaGel® resins. The spacer is in the range of MW 1500 - 2000 Da.

貨號	名稱	particle size	capacity	包裝
HL 12 016	TentaGel® HL FMP	75 µm	0.3 - 0.4 mmol/g	1g
HL 12 016	TentaGel® HL FMP	75 µm	0.3 - 0.4 mmol/g	5g
HL 12 016	TentaGel® HL FMP	75 µm	0.3 - 0.4 mmol/g	25g
HL 12 016	TentaGel® HL FMP	75 µm	0.3 - 0.4 mmol/g	100g

B7.6.1.3.2 TentaGel® MB FMP TentaGel Macrobeads Modified with FMP Linker

貨號	名稱	particle size	capacity	包裝
MB 160 160	TentaGel® MB FMP	140 - 170 µm	0.35 - 0.45	1g
MB 160 160	TentaGel® MB FMP	140 - 170 µm	0.35 - 0.45	5g
MB 160 160	TentaGel® MB FMP	140 - 170 µm	0.35 - 0.45	25g
MB 160 160	TentaGel® MB FMP	140 - 170 µm	0.35 - 0.45	100g
MB 250 160	TentaGel® MB FMP	200 - 250 µm	0.2 - 0.3	1g
MB 250 160	TentaGel® MB FMP	200 - 250 µm	0.2 - 0.3	5g
MB 250 160	TentaGel® MB FMP	200 - 250 µm	0.2 - 0.3	25g
MB 250 160	TentaGel® MB FMP	200 - 250 µm	0.2 - 0.3	100g
MB 300 160	TentaGel® MB FMP	280 - 320 µm	0.2 - 0.3	1g
MB 300 160	TentaGel® MB FMP	280 - 320 µm	0.2 - 0.3	5g
MB 300 160	TentaGel® MB FMP	280 - 320 µm	0.2 - 0.3	25g
MB 300 160	TentaGel® MB FMP	280 - 320 µm	0.2 - 0.3	100g

B7.6.1.3.3 TentaGel® S FMP Standard TentaGel Resins Modified with FMP Linker

貨號	名稱	particle size	capacity	包裝
S 30 016	TentaGel® S FMP	90 µm	0.2 - 0.25	1g
S 30 016	TentaGel® S FMP	90 µm	0.2 - 0.25	5g
S 30 016	TentaGel® S FMP	90 µm	0.2 - 0.25	25g
S 30 016	TentaGel® S FMP	90 µm	0.2 - 0.25	100g

B7.6.2 Polystyrene based Resins
B7.6.2.1 4-Formyl Phenoxyethyl Polystyrene Resins (FP-Linker, 4-Alkoxybenzaldehyd resin)

貨號	名稱	particle size	capacity	包裝
HA 1 100 07	Polystyrene A FP	100 - 200 mesh	0.7 - 1.1 mmol/g	5g
HA 1 100 07	Polystyrene A FP	100 - 200 mesh	0.7 - 1.1 mmol/g	25g
HA 1 100 07	Polystyrene A FP	100 - 200 mesh	0.7 - 1.1 mmol/g	100g
HA 1 400 07	Polystyrene A FP	200 - 400 mesh	0.7 - 1.1 mmol/g	5g
HA 1 400 07	Polystyrene A FP	200 - 400 mesh	0.7 - 1.1 mmol/g	25g
HA 1 400 07	Polystyrene A FP	200 - 400 mesh	0.7 - 1.1 mmol/g	100g
HA 125160 07	Polystyrene A FP	125 - 160 µm	0.7 - 1.1 mmol/g	5g
HA 125160 07	Polystyrene A FP	125 - 160 µm	0.7 - 1.1 mmol/g	25g
HA 125160 07	Polystyrene A FP	125 - 160 µm	0.7 - 1.1 mmol/g	100g
HA 160200 07	Polystyrene A FP	160 - 200 µm	0.7 - 1.1 mmol/g	5g
HA 160200 07	Polystyrene A FP	160 - 200 µm	0.7 - 1.1 mmol/g	25g
HA 160200 07	Polystyrene A FP	160 - 200 µm	0.7 - 1.1 mmol/g	100g
HA 250315 07	Polystyrene A FP	250 - 315 µm	0.5 - 0.8 mmol/g	5g
HA 250315 07	Polystyrene A FP	250 - 315 µm	0.5 - 0.8 mmol/g	25g
HA 250315 07	Polystyrene A FP	250 - 315 µm	0.5 - 0.8 mmol/g	100g
HA 400450 07	Polystyrene A FP	400 - 450 µm	0.5 - 0.8 mmol/g	5g
HA 400450 07	Polystyrene A FP	400 - 450 µm	0.5 - 0.8 mmol/g	25g
HA 400450 07	Polystyrene A FP	400 - 450 µm	0.5 - 0.8 mmol/g	100g
HA 500560 07	Polystyrene A FP	500 - 560 µm	0.5 - 0.8 mmol/g	5g
HA 500560 07	Polystyrene A FP	500 - 560 µm	0.5 - 0.8 mmol/g	25g
HA 500560 07	Polystyrene A FP	500 - 560 µm	0.5 - 0.8 mmol/g	100g

B7.6.2.2 4-Formyl-3-Methoxy Phenoxybutyl Polystyrene Resins (FMP-Linker)

貨號	名稱	particle size	capacity	包裝
HB 045080 08	Polystyrene C4 FMP	45 - 80 µm	0.7 - 1.0 mmol/g	5g
HB 045080 08	Polystyrene C4 FMP	45 - 80 µm	0.7 - 1.0 mmol/g	25g
HB 045080 08	Polystyrene C4 FMP	45 - 80 µm	0.7 - 1.0 mmol/g	100g
HB 080160 08	Polystyrene C4 FMP	80 - 160 µm	0.7 - 1.0 mmol/g	5g
HB 080160 08	Polystyrene C4 FMP	80 - 160 µm	0.7 - 1.0 mmol/g	25g
HB 080160 08	Polystyrene C4 FMP	80 - 160 µm	0.7 - 1.0 mmol/g	100g
HB 125160 08	Polystyrene C4 FMP	125 - 160 µm	0.7 - 1.0 mmol/g	5g
HB 125160 08	Polystyrene C4 FMP	125 - 160 µm	0.7 - 1.0 mmol/g	25g
HB 125160 08	Polystyrene C4 FMP	125 - 160 µm	0.7 - 1.0 mmol/g	100g

B7.6.2.3 4-Formyl-3-Methoxy Phenoxyethyl Polystyrene Resins (FMP-Linker)

貨號	名稱	particle size	capacity	包裝
HA 1 100 08	Polystyrene A FMP	100 - 200 mesh	0.7 - 1.1 mmol/g	5g
HA 1 100 08	Polystyrene A FMP	100 - 200 mesh	0.7 - 1.1 mmol/g	25g
HA 1 100 08	Polystyrene A FMP	100 - 200 mesh	0.7 - 1.1 mmol/g	100g
HA 1 400 08	Polystyrene A FMP	200 - 400 mesh	0.7 - 1.1 mmol/g	5g
HA 1 400 08	Polystyrene A FMP	200 - 400 mesh	0.7 - 1.1 mmol/g	25g
HA 1 400 08	Polystyrene A FMP	200 - 400 mesh	0.7 - 1.1 mmol/g	100g
HA 125160 08	Polystyrene A FMP	125 - 160 µm	0.7 - 1.1 mmol/g	5g
HA 125160 08	Polystyrene A FMP	125 - 160 µm	0.7 - 1.1 mmol/g	25g
HA 125160 08	Polystyrene A FMP	125 - 160 µm	0.7 - 1.1 mmol/g	100g
HA 160200 08	Polystyrene A FMP	160 - 200 µm	0.7 - 1.1 mmol/g	5g
HA 160200 08	Polystyrene A FMP	160 - 200 µm	0.7 - 1.1 mmol/g	25g
HA 160200 08	Polystyrene A FMP	160 - 200 µm	0.7 - 1.1 mmol/g	100g
HA 250315 08	Polystyrene A FMP	250 - 315 µm	0.5 - 0.8 mmol/g	5g
HA 250315 08	Polystyrene A FMP	250 - 315 µm	0.5 - 0.8 mmol/g	25g
HA 250315 08	Polystyrene A FMP	250 - 315 µm	0.5 - 0.8 mmol/g	100g
HA 400450 08	Polystyrene A FMP	400 - 450 µm	0.5 - 0.8 mmol/g	5g
HA 400450 08	Polystyrene A FMP	400 - 450 µm	0.5 - 0.8 mmol/g	25g
HA 400450 08	Polystyrene A FMP	400 - 450 µm	0.5 - 0.8 mmol/g	100g
HA 500560 08	Polystyrene A FMP	500 - 560 µm	0.5 - 0.8 mmol/g	5g
HA 500560 08	Polystyrene A FMP	500 - 560 µm	0.5 - 0.8 mmol/g	25g
HA 500560 08	Polystyrene A FMP	500 - 560 µm	0.5 - 0.8 mmol/g	100g

B7.7 Resins with Base Labile Linkers

B7.7.1 Polar PEG Spacer Resins with Base Labile Linkers
B7.7.1.1 4-(Hydroxymethyl) Benzoic Acid (HMBA) on HypoGel® Resins
HypoGel® is a hydrophilic gel type resin which combines high capacities with good solvent compatibility. Glycol spacers with n = 5 or 10 EO units separate the reactive sites from the polystyrene matrix and modify the hydrophobic properties of the polystyrene backbone. Due to the spacer effect the functional group shows a higher mobility which results in higher kinetic rates and high resolution NMR spectra from immobilized compounds on the bead. The resin is compatible to a wide range of solvents and in contrast to polystyrene even polar solvents like methanol or ethanol can be used.
These resins show high loading and a hydrophilicity between polystyrene and TentaGel®
This resin is derived from HypoGel® amine and the base labile 4-(hydroxymethyl)benzoic acid linker. It is a versatile support for the immobilization of carboxylic acids. The resulting ester bond is stable to strong acids but is cleaved by nucleophiles like amines, hydrazine or alkoxides.
Literature
L 17

貨號	名稱	particle size	capacity	包裝
SP200 110150 140	HypoGel® 200 HMBA	110 - 150 µm	0.6 - 0.8 mmol/g	5g
SP200 110150 140	HypoGel® 200 HMBA	110 - 150 µm	0.6 - 0.8 mmol/g	25g
SP200 110150 140	HypoGel® 200 HMBA	110 - 150 µm	0.6 - 0.8 mmol/g	100g
SP400 110150 140	HypoGel® 400 HMBA	110 - 150 µm	0.4 - 0.6 mmol/g	5g
SP400 110150 140	HypoGel® 400 HMBA	110 - 150 µm	0.4 - 0.6 mmol/g	25g
SP400 110150 140	HypoGel® 400 HMBA	110 - 150 µm	0.4 - 0.6 mmol/g	100g

B7.7.1.2 4-(Hydroxymethyl) Benzoic Acid (HMBA) on TentaGel® Resins
B7.7.1.2.1 TentaGel® HL HMBA HMBA Linker Attached to High Loaded TentaGel Resins

貨號	名稱	particle size	capacity	包裝
HL12 014	TentaGel® HL HMBA	75 µm	0.3 - 0.4 mmol/g	1g
HL12 014	TentaGel® HL HMBA	75 µm	0.3 - 0.4 mmol/g	5g
HL12 014	TentaGel® HL HMBA	75 µm	0.3 - 0.4 mmol/g	25g
HL12 014	TentaGel® HL HMBA	75 µm	0.3 - 0.4 mmol/g	50g

B7.7.1.2.2 TentaGel® MB HMBA HMBA Linker Attached to TentaGel Macrobeads

貨號	名稱	particle size	capacity	包裝
MB 160 140	TentaGel® MB HMBA	140 - 170 µm	0.4 - 0.5 mmol/g	1g
MB 160 140	TentaGel® MB HMBA	140 - 170 µm	0.4 - 0.5 mmol/g	5g
MB 160 140	TentaGel® MB HMBA	140 - 170 µm	0.4 - 0.5 mmol/g	25g
MB 160 140	TentaGel® MB HMBA	140 - 170 µm	0.4 - 0.5 mmol/g	50g
MB 250 140	TentaGel® MB HMBA	200 - 250 µm	0.2 - 0.3 mmol/g	1g
MB 250 140	TentaGel® MB HMBA	200 - 250 µm	0.2 - 0.3 mmol/g	5g
MB 250 140	TentaGel® MB HMBA	200 - 250 µm	0.2 - 0.3 mmol/g	25g
MB 250 140	TentaGel® MB HMBA	200 - 250 µm	0.2 - 0.3 mmol/g	50g
MB 300 140	TentaGel® MB HMBA	280 - 320 µm	0.2 - 0.3 mmol/g	1g
MB 300 140	TentaGel® MB HMBA	280 - 320 µm	0.2 - 0.3 mmol/g	5g
MB 300 140	TentaGel® MB HMBA	280 - 320 µm	0.2 - 0.3 mmol/g	25g
MB 300 140	TentaGel® MB HMBA	280 - 320 µm	0.2 - 0.3 mmol/g	50g

B7.7.1.2.3 TentaGel® R HMBA HMBA Linker Attached to TentaGel Research Resins

貨號	名稱	particle size	capacity	包裝
R 28 023	TentaGel® R HMBA	90 µm	0.18 - 0.22 mmol/g	1g
R 28 023	TentaGel® R HMBA	90 µm	0.18 - 0.22 mmol/g	5g
R 28 023	TentaGel® R HMBA	90 µm	0.18 - 0.22 mmol/g	25g
R 28 023	TentaGel® R HMBA	90 µm	0.18 - 0.22 mmol/g	50g

B7.7.1.2.4 TentaGel® S HMBA HMBA Linker Attached to Standard TentaGel Resins

貨號	名稱	particle size	capacity	包裝
S 30 014	TentaGel® S HMBA	90 µm	0.2 - 0.28 mmol/g	1g
S 30 014	TentaGel® S HMBA	90 µm	0.2 - 0.28 mmol/g	5g
S 30 014	TentaGel® S HMBA	90 µm	0.2 - 0.28 mmol/g	25g
S 30 014	TentaGel® S HMBA	90 µm	0.2 - 0.28 mmol/g	50g

B7.7.2 Polystyrene Resins with Base Labile Linkers
B7.7.2.1 4-(Hydroxymethyl) Benzoic Acid (HMBA) on Aminoethyl Polystyrene

貨號	名稱	particle size	capacity	包裝
HA 1 100 14	Polystyrene A HMBA	100 - 200 mesh	0.8 - 1.2 mmol/g	5g
HA 1 100 14	Polystyrene A HMBA	100 - 200 mesh	0.8 - 1.2 mmol/g	25g
HA 1 100 14	Polystyrene A HMBA	100 - 200 mesh	0.8 - 1.2 mmol/g	100g
HA 1 400 14	Polystyrene A HMBA	200 - 400 mesh	0.8 - 1.2 mmol/g	5g
HA 1 400 14	Polystyrene A HMBA	200 - 400 mesh	0.8 - 1.2 mmol/g	25g
HA 1 400 14	Polystyrene A HMBA	200 - 400 mesh	0.8 - 1.2 mmol/g	100g
HA 125160 14	Polystyrene A HMBA	125 - 160 µm	0.8 - 1.2 mmol/g	5g
HA 125160 14	Polystyrene A HMBA	125 - 160 µm	0.8 - 1.2 mmol/g	25g
HA 125160 14	Polystyrene A HMBA	125 - 160 µm	0.8 - 1.2 mmol/g	100g
HA 160200 14	Polystyrene A HMBA	160 - 200 µm	0.8 - 1.2 mmol/g	5g
HA 160200 14	Polystyrene A HMBA	160 - 200 µm	0.8 - 1.2 mmol/g	25g
HA 160200 14	Polystyrene A HMBA	160 - 200 µm	0.8 - 1.2 mmol/g	100g
HA 250315 14	Polystyrene A HMBA	250 - 315 µm	0.6 - 1.0 mmol/g	5g
HA 250315 14	Polystyrene A HMBA	250 - 315 µm	0.6 - 1.0 mmol/g	25g
HA 250315 14	Polystyrene A HMBA	250 - 315 µm	0.6 - 1.0 mmol/g	100g
HA 400450 14	Polystyrene A HMBA	400 - 450 µm	0.6 - 1.0 mmol/g	5g
HA 400450 14	Polystyrene A HMBA	400 - 450 µm	0.6 - 1.0 mmol/g	25g
HA 400450 14	Polystyrene A HMBA	400 - 450 µm	0.6 - 1.0 mmol/g	100g
HA 500560 14	Polystyrene A HMBA	500 - 560 µm	0.6 - 1.0 mmol/g	5g
HA 500560 14	Polystyrene A HMBA	500 - 560 µm	0.6 - 1.0 mmol/g	25g
HA 500560 14	Polystyrene A HMBA	500 - 560 µm	0.6 - 1.0 mmol/g	100g

B7.7.2.2 4-(Hydroxymethyl) Benzoic Acid (HMBA) on Aminomethyl Polystyrene

貨號	名稱	particle size	capacity	包裝
H 1 100 14	Polystyrene AM HMBA	100 - 200 mesh	0.8 - 1.2 mmol/g	5g
H 1 100 14	Polystyrene AM HMBA	100 - 200 mesh	0.8 - 1.2 mmol/g	25g
H 1 100 14	Polystyrene AM HMBA	100 - 200 mesh	0.8 - 1.2 mmol/g	100g
H 1 400 14	Polystyrene AM HMBA	200 - 400 mesh	0.8 - 1.2 mmol/g	5g
H 1 400 14	Polystyrene AM HMBA	200 - 400 mesh	0.8 - 1.2 mmol/g	25g
H 1 400 14	Polystyrene AM HMBA	200 - 400 mesh	0.8 - 1.2 mmol/g	100g
H 125160 14	Polystyrene AM HMBA	125 - 160 µm	0.8 - 1.2 mmol/g	5g
H 125160 14	Polystyrene AM HMBA	125 - 160 µm	0.8 - 1.2 mmol/g	25g
H 125160 14	Polystyrene AM HMBA	125 - 160 µm	0.8 - 1.2 mmol/g	100g
H 160200 14	Polystyrene AM HMBA	160 - 200 µm	0.8 - 1.2 mmol/g	5g
H 160200 14	Polystyrene AM HMBA	160 - 200 µm	0.8 - 1.2 mmol/g	25g
H 160200 14	Polystyrene AM HMBA	160 - 200 µm	0.8 - 1.2 mmol/g	100g
H 250315 14	Polystyrene AM HMBA	250 - 315 µm	0.6 - 1.0 mmol/g	5g
H 250315 14	Polystyrene AM HMBA	250 - 315 µm	0.6 - 1.0 mmol/g	25g
H 250315 14	Polystyrene AM HMBA	250 - 315 µm	0.6 - 1.0 mmol/g	100g
H 400450 14	Polystyrene AM HMBA	400 - 450 µm	0.6 - 1.0 mmol/g	5g
H 400450 14	Polystyrene AM HMBA	400 - 450 µm	0.6 - 1.0 mmol/g	25g
H 400450 14	Polystyrene AM HMBA	400 - 450 µm	0.6 - 1.0 mmol/g	100g
H 500560 14	Polystyrene AM HMBA	500 - 560 µm	0.6 - 1.0 mmol/g	5g
H 500560 14	Polystyrene AM HMBA	500 - 560 µm	0.6 - 1.0 mmol/g	25g
H 500560 14	Polystyrene AM HMBA	500 - 560 µm	0.6 - 1.0 mmol/g	100g

²B8 Scavenger Resins and Polymer Bound Reagents

B8.1 Polymer Supported Protecting Groups

B8.1.1 Bromo Acetal Resins
B8.1.1.1 Bromoacetal Linker on HypoGel® Resins

貨號	名稱	particle size	capacity	包裝
SP200 110150 190	HypoGel® 200 Bromo Acetal	110 - 150 µm	0.75 - 0.95 mmol/g	5g
SP200 110150 190	HypoGel® 200 Bromo Acetal	110 - 150 µm	0.75 - 0.95 mmol/g	25g
SP200 110150 190	HypoGel® 200 Bromo Acetal	110 - 150 µm	0.75 - 0.95 mmol/g	100g
SP400 110150 190	HypoGel® 400 Bromo Acetal	110 - 150 µm	0.6 - 0.8 mmol/g	5g
SP400 110150 190	HypoGel® 400 Bromo Acetal	110 - 150 µm	0.6 - 0.8 mmol/g	25g
SP400 110150 190	HypoGel® 400 Bromo Acetal	110 - 150 µm	0.6 - 0.8 mmol/g	100g

B8.1.1.2 Bromoacetal Linker on TentaGel® Resins

貨號	名稱	particle size	capacity	包裝
HL 12 019	TentaGel® HL Bromo Acetal	75 µm	0.4 - 0.55 mmol/g	5g
HL 12 019	TentaGel® HL Bromo Acetal	75 µm	0.4 - 0.55 mmol/g	25g
HL 12 019	TentaGel® HL Bromo Acetal	75 µm	0.4 - 0.55 mmol/g	100g

B8.1.2 Diol Resins
B8.1.2.1 HypoGel® Diol

貨號	名稱	particle size	capacity	包裝
SP200 110150 10	HypoGel® 200 Diol	110 - 150 µm	1.2 - 1.5 mmol/g	5g
SP200 110150 10	HypoGel® 200 Diol	110 - 150 µm	1.2 - 1.5 mmol/g	25g
SP200 110150 10	HypoGel® 200 Diol	110 - 150 µm	1.2 - 1.5 mmol/g	100g
SP400 110150 10	HypoGel® 400 Diol	110 - 150 µm	0.9 - 1.3 mmol/g	5g
SP400 110150 10	HypoGel® 400 Diol	110 - 150 µm	0.9 - 1.3 mmol/g	25g
SP400 110150 10	HypoGel® 400 Diol	110 - 150 µm	0.9 - 1.3 mmol/g	100g

B8.1.2.2 TentaGel® Diol

貨號	名稱	particle size	capacity	包裝
HL 12 01	TentaGel® HL Diol	75 µm	0.6 - 0.8 mmol/g	5g
HL 12 01	TentaGel® HL Diol	75 µm	0.6 - 0.8 mmol/g	25g
HL 12 01	TentaGel® HL Diol	75 µm	0.6 - 0.8 mmol/g	100g

B8.2 Scavenger Resins - ScavengePore®

貨號	名稱	capacity	包裝
SC11011	ScavengePore® Benzenesulfonic acid, Na+-form	1 - 2 mmol/g	10g
SC11011	ScavengePore® Benzenesulfonic acid, Na+-form	1 - 2 mmol/g	100g
SC11012	ScavengePore® Benzyltriethylammonium chloride	0.5 - 1 mmol/g	10g
SC11012	ScavengePore® Benzyltriethylammonium chloride	0.5 - 1 mmol/g	100g
SC11013	ScavengePore® Benzoic Acid	0.5 - 2.0 mmol/g	5g
SC11013	ScavengePore® Benzoic Acid	0.5 - 2.0 mmol/g	25g
SC11014	ScavengePore® Benzenesulfonic acid, H+-form	1 - 2 mmol/g	10g
SC11014	ScavengePore® Benzenesulfonic acid, H+-form	1 - 2 mmol/g	100g
SC11102	ScavengePore® Benzylamine	0.5 - 1.5 mmol/g and 2 - 3.5 mmol/g	5g
SC11102	ScavengePore® Benzylamine	0.5 - 1.5 mmol/g and 2 - 3.5 mmol/g	25g
SC11103	ScavengePore® Benzyl Isocyanate	0.5 - 1.1 mmol/g	5g
SC11103	ScavengePore® Benzyl Isocyanate	0.5 - 1.1 mmol/g	25g
SC11207	ScavengePore® 4-Phenethyloxybenzaldehyde	0.5 - 1.2 mmol/g	5g
SC11207	ScavengePore® 4-Phenethyloxybenzaldehyde	0.5 - 1.2 mmol/g	25g
SC11208	ScavengePore® Phenethyldiethylamine	0.5 - 1.5 mmol/g	5g
SC11208	ScavengePore® Phenethyldiethylamine	0.5 - 1.5 mmol/g	25g
SC11209	ScavengePore® Phenethylmorpholine	0.5 - 1.2 mmol/g	5g
SC11209	ScavengePore® Phenethylmorpholine	0.5 - 1.2 mmol/g	25g
SC11210	ScavengePore® Phenethylpiperidine	0.5 - 1.2 mmol/g	5g
SC11210	ScavengePore® Phenethylpiperidine	0.5 - 1.2 mmol/g	25g

B8.3 Triphenylphosphine Resins

B8.3.1 Polymer Supported Palladium

貨號	名稱	capacity	包裝
HR 100 31-Pd	Polystyrene-Tetrakis (Triphenylphosphine) Palladium	100 - 200 mesh	1g
HR 100 31-Pd	Polystyrene-Tetrakis (Triphenylphosphine) Palladium	100 - 200 mesh	5g

B8.3.2 Polystyrene Triphenylphosphine

貨號	名稱	particle size	capacity	包裝
HR 100 31-0	Polystyrene-Triphenylphosphine	100 - 200 mesh	1 - 1.5 mmol/g	5g
HR 100 31-0	Polystyrene-Triphenylphosphine	100 - 200 mesh	1 - 1.5 mmol/g	25g
HR 100 31-0	Polystyrene-Triphenylphosphine	100 - 200 mesh	1 - 1.5 mmol/g	100g
HR 400 31-0	Polystyrene-Triphenylphosphine	200 - 400 mesh	1 - 1.5 mmol/g	5g
HR 400 31-0	Polystyrene-Triphenylphosphine	200 - 400 mesh	1 - 1.5 mmol/g	25g
HR 400 31-0	Polystyrene-Triphenylphosphine	200 - 400 mesh	1 - 1.5 mmol/g	100g